Immunopharmacologist, Vaccine Research (R3-R4) Job in La Jolla, California US
Immunopharmacologist, Vaccine Research (R3-R4)
Org Marketing Statement Pfizer Inc: Working together for a healthier world Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide. Job Focus Vaccine Research seeks to discover novel vaccines (prophylactic and therapeutic) for the prevention and treatment of significant human diseases (infectious diseases, oncology, CNS and Allergy and Respiratory) using a variety of vaccine technology platforms combined with immunomodulatory agents. Individuals with experience of in vivo experimentation are required to join the expanding Vaccine Research West group in La Jolla, California. The candidate will have deep knowledge and practical experience of the application of techniques suitable for assessing in vivo immune parameters. They will be able to independently and proactively apply this knowledge in the design and execution of experimental work, to enable progression of vaccine discovery projects. Experience in the following areas is essential: (1) in vivo protocols including dosing techniques and tissue sampling. (2) Experience of standard microbiological techniques, safe handling of pathogenic microorganisms or radioisotopes. (3) Animal models of disease, especially neurological, bacterial and virological. (4) Immunoassay work. The candidate will be required to work independently and, as a member of a project team, be accountable for the critical appraisal of their results and regularly present them for review at team meetings and for specific project milestones. The role is primarily laboratory based. Responsibilities Laboratory and related work (70 % of time) - Experimental design - will help design and fine tune in vivo experiments following discussion with supervisor and literature review. Will then independently (or as part of a team) execute work following the plan. Will analyze, interpret, record and communicate experimental data. Will have / gain skills and experience to be fully conversant with the operation and validation of all items of equipment or IT needed for experimentation, data analysis, storage and data entry. Understand and improve the in vivo ""model"" in use, and its relevance to the project. Documentation and Communication - Writing standard operating procedures, study reports and protocols Write up laboratory notebooks regularly in compliance with GSP or GLP if relevant. Presentation to immunopharmacology and project teams Regular 1:1 communication with supervisor and team colleagues. Safe working and regulatory compliance - Work safely themselves. Including work (potentially) with pathogenic microorganisms, hazardous materials or radioactive substances Completion of risk assessments, compliance with PGRD procedures Adherence to risk assessments Will recognize risks (own and others), within own area of expertise. Intervene or take action, where appropriate Understand ethical considerations associated with using animals in biomedical research Qualifications Training Education Minimum Requirements: BSc in life sciences, preferably including immunology, microbiology and neuroscience elements Minimum of 5 years in vivo pharmacology experience Significant experience of hands-on in vivo work (full range of procedures). Setting up / running animal models of disease Overall responsibility for management of in vivo work-streams within research project(s) Excellent pre-planning, organizational and trouble shooting skills Ability to communicate effectively, including with external stakeholders, vendors, suppliers etc Immune cell purification and characterization Safe handling of microorganisms and radioisotopes Antibody and cell-based ex vivo assays Virology and bacteriology techniques Preferred: Neuroscience animal modeling experience molecular approaches (e.g. PCR) Histological procedures Immunostaining techniques Equal Employment Opportunity Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer. *This job post was placed on PharmaDiversity Job Board with permission of this employer. If viewing this post anywhere else, the "apply" click should lead you to PharmaDiversity Job Board for authentic job post view with direct employer application. For application attention if web source is requested please use "PharmaDiversity" or "PharmaDiversity Job Board". Pfizer prefers that you apply to this job directly on their site