Senior Scientist/Principal Scientist

Senior Scientist/Principal Scientist - Research Formulations

Org Marketing Statement Pfizer Inc: Working together for a healthier world Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide. Responsibilities A position in the Formulation Design Development group to evaluate physical and biophysical properties of organic compounds relevant to oral drug delivery. Responsibilities include the design and supervision of laboratory studies aimed at development of new dosage forms, particularly oral immediate release and controlled release dosage forms. Provides scientific guidance and direction to the department on project and new scientific technology concepts. Develop and use advanced modeling tools for predictive performance of formulations in achieving desirable delivery profiles. Use knowledge of permeability and transport to optimize early stage formulations. Design experiments to develop novel formulations for administration of drug candidates to animals and humans. Perform laboratory experiments related to the above areas as well as effectively mentor and develop other scientists. Interface with, provide formulation knowledge and expertise, and communicate the interpretation and implication of results to drug discovery teams and Pharmaceutical Science project teams. In addition, proficiently interfaces with other departments on projects and can represent both our department and technical aspects of dosage form development to various governance bodies. Design and lead drug delivery research programs that benefit both Pfizer and the broader scientific community. Maintain an awareness of and contribute to current scientific literature; actively apply new concepts as appropriate. Conduct novel scientific research and present significant findings via internal and external presentations or publications. Qualifications EDUCATIONAL BACKGROUND: MS + 3-5 year experience or PhD + 1 year of experience in Pharmaceutics, Chemistry, Biochemistry, Chemical Engineering, or Biophysics WORK EXPERIENCE/SKILLS: Experience in biopharmaceutics modeling, biological transport phenomena, interpretation and use of in-vitro permeability measurements, or in-vivo/in-vitro drug metabolism studies. Facility with computational chemistry tools to predict physical properties. Strong organizational skills, interpersonal, written, and verbal communication skills. Experience in formulation development, preformulation studies, or demonstrated capability with pharmacokinetic models for predicting exposure following oral delivery. Application of fundamental principles to predict and solve chemical stability issues in formulations. Knowledge or experience in later stage formulation development. Background in appropriate programming languages (e.g., MatLab, Visual Basic, Java). Strong scientific leadership and direction of new technology initiatives. Equal Employment Opportunity Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer. *This job post was placed on PharmaDiversity Job Board with permission of this employer. If viewing this post anywhere else, the "apply" click should lead you to PharmaDiversity Job Board for authentic job post view with direct employer application. For application attention if web source is requested please use "PharmaDiversity" or "PharmaDiversity Job Board". Pfizer prefers that you apply to this job directly on their site